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Abstract
- 1.1. Animal experimentation conducted on 36 dogs indicates that an increase either in the number or the virulence of bacteria in gall-bladder bile using a non-traumatizing technique, seldomly produces a reaction in the gall-bladder wall. A severe infection of the wall was obtained in 3 dogs, which had been injected with one particular strain of Streptococcus hemolyticus. The gall-bladder wall remained practically unchanged, however, upon the injection of three other strains of Streptococcus hemolyticus, as well as Bacillus coli, Streptococcus viridans, Staphylococcus aureus and albus, and Bacillus Welchii.
- 2.2. In many cases the same organisms injected directly through the gall-bladder wall, or with an accompanying ligation of the common or cystic duct, produce severe or even fatal cholecystitis.
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Footnotes
☆Work done in part under a grant from the Douglas Smith Foundation.
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© 1936 Published by Elsevier Inc.
