Rapid Communication| Volume 32, ISSUE 3, P411-416, June 1936

Rectal administration of evipal soluble

A safe, reversible and controllable preanesthetic medication a preliminary report
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      • 1.
        1. Since using dilaudid there has been no occurrence of nausea and vomiting, as compared to 16 per cent of the patients who were nauseated when morphine hydrochloride was used.
      • 2.
        2. The index of 0.2 c.c. per pound body weighed holds good for all ages. The youngest patient was three years of age, and weighed thirty pounds, received 6 c.c. of a 10 per cent solution of evipal soluble, which was entirely satisfactory. The oldest patient who was eighty-five years of age and weighed 150 pounds, received 3 gm. or 30 c.c. of a 10 per cent solution.
      • 3.
        3. Rectal evipal soluble given in the patient's own bed abolishes mental fear as well as physical pain.
      • 4.
        4. Both laboratory and clinical experience demonstrate the value of safe preanesthetic medication. Rectal administration of evipal soluble in the dosage stated makes inhalation, local or spinal anesthesia safer for the patient and easier for the surgeon. Evipal soluble may be given rectally in cases in which intravenous anesthesia is contraindicated because of the fear aroused in nervous patients or the difficulty encountered in entering a vein as in children and obese individuals.
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