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Background
Endoscopic ultrasound (EUS) with EUS-guided fine-needle aspiration (EUS-FNA) enables
one to visualize the pancreas and surrounding structures and can provide access for
FNA of those structures that appear suspicious for tumor.
Patients and methods
From 1993 to 1995, 50 patients suspected of having pancreatic cancer underwent EUS/EUS-FNA
and abdominal computed tomography (CT). Malignancy was found in 30 (60%) cases, which
included 24 (48%) pancreatic adenocarcinomas.
Results
Endoscopic ultrasound/EUS-FNA identified 26 of the 30 malignancies (85%) and 21 of
the 24 pancreatic adenocarcinomas (88%), with no false positives. Thirteen of the
24 pancreatic cancer patients had lymph nodes that were sampled with EUS/EUS-FNA.
Seven of these 13 patients (62%) were found to have metastatic spread to lymph nodes.
Operations were performed on 11 of the pancreatic cancer patients. Of these 11, the
5 that were predicted to be resectable by EUS/EUS-FNA underwent successful resection.
Of the 6 predicted to be unresectable, 5 had palliative biliary bypasses, and 1 had
a grossly positive margin of resection.
Conclusions
Endoscopic ultrasound/EUS-FNA can identify patients for curative surgical resection.
It can also preoperatively identify patients with regional nodal disease for inclusion
in appropriately designed clinical trials.
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References
- Preoperative staging and assessment of resectability of pancreatic cancer.Arch Surg. 1990; 125: 230-233
- Pancreaticoduodenectomy for cancer of the head of the pancreas, 201 patients.Ann Surg. 1995; 221: 721-733
- Survival after pancreaticoduodenectomy: 118 consecutive resections without an operative mortality.Ann Surg. 1990; 211: 447-458
- Assessment of resectability of carcinoma of the pancreatic head by ultrasonography and computed tomography, a retrospective analysis.Eur J Surg Oncol. 1990; 16: 411-416
- How accurate is size measurement of pancreas cancer by computed axial tomography.Am Surg. 1995; 61: 686-691
- A comparison of ultrasound, computed tomography and endoscopic retrograde cholangiopancreatography in the differential diagnosis of benign and malignant jaundice and cholestasis.Eur J Surg. 1993; 159: 23-29
- Cytological brushings of ductal lesions during ERCP.Gastromtes Endosc. 1991; 37: 139-142
- Endoscopic ultrasonography compared with computed tomography and ERCP in patients with obstructive jaundice or peri-pancreatic mass.Gastrointes Endosc. 1992; 38: 27-34
- Staging of pancreatic and ampullary cancer by endoscopy.Endoscopy. 1993; 25: 52-57
- Endoscopic ultrasonography in the differential diagnosis of pancreatic disease.Gastrointes Endos. 1989; 35: 214-219
- Endoscopic ultrasonography in the diagnosis and staging of pancreatic adenocarcinoma. Results of a prospective study with comparison to ultrasonography and CT scan.Endoscopy. 1993; 25: 143-150
- Staging of pancreatic and ampullary carcinoma by endoscopic ultrasonography.Gostroenterology. 1992; 102: 188-199
- Endoscopic ultrasound-guided fine-needle aspirate.Gastrointest Endosc. 1994; 40: 694-699
- Endoscopic ultrasound guided fine needle aspiration in the diagnosis and staging of pancreatic tumors.Gastro Endosc Clinics N Am. 1995; 5: 723-733
Article info
Footnotes
**Presented at the 48th Annual Meeting of the Southwestern Surgical Congress, Scottsdale, Arizona, April 28–May 1, 1996.
Identification
Copyright
© 1996 Excerpta Medica, Inc. All rights reserved. Published by Elsevier Inc.
