Advertisement
Research Article| Volume 172, ISSUE 5, P487-490, November 1996

T1 breast carcinoma in women 70 years of age and older may not require axillary lymph node dissection

      This paper is only available as a PDF. To read, Please Download here.

      Background

      The current trend in breast cancer treatment is toward breast conservation and selective use of axillary lymph node dissection. Patient eligiblity criteria for treatment without axillary dissection are evolving.

      Methods

      We retrospectively reviewed the tumor registry over a 10-year period at Naval Medical Center San Diego and included all women aged 70 and older with T1 breast carcinoma (n = 78). Data included tumor size, surgical therapy, postoperative therapy, recurrence, and survival. The women were divided into groups by the approach taken toward the axilla.

      Results

      No patient was given adjuvant chemotherapy. There were no axillary cancer recurrences in our patients. No statistically significant difference existed, regardless of the approach to the axilla, in recurrence or survival between groups.

      Conclusion

      Axillary dissection in this population did not influence postoperative treatment, decrease recurrence, or improve survival. Our study suggests breast cancer treatment in this populationshould not include axillary dissection.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to The American Journal of Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Fischer B
        • Bauer M
        • Margolese R
        • et al.
        Five year results of a randomized clinical trial comparing total mastectomy and segmental mastectomy with or without radiation in treatment of cancer.
        NEJM. 1985; 312: 665-673
        • Lin P
        • Allison D
        • Wainstock J
        • et al.
        Impact of axillary lymph node dissection on the therapy of breast cancer patients.
        J Clin Oncol. 1993; 11: 1536-1544
        • Siegel B
        • Mayzel K
        • Love S
        Level I and II axillar? dissection in the treatment of early-stage breast cancer.
        Arch Surg. 1990; 125: 1144-1147
        • Haffty J
        • McKhann C
        • Beinfield M
        • et al.
        Breast conservation therapy without axillary dissection.
        Arch Surg. 1993; 128: 1315-1319
        • Silverstein M
        • Gierson E
        • Waisman J
        • et al.
        Axillary lymph node dissection for T1a breast carcinoma: is it indicated?.
        Cancer. 1994; 73: 664-667
        • Reger V
        • Beito G
        • Jolly P
        Factors affecting the incidence of lymph node metastases in small cancers of the breast.
        Am J Surg. 1989; 157: 501-502
        • Sauer R
        • Schauer A
        • Rauschecker H
        • et al.
        Therapy of small breast cancer: a prospective study on 1036 patients with a special emphasis on prognostic factors.
        Int J Rad Oncol. 1992; 23: 907-914
        • Von Rueden D
        • Sessions S
        Alternative therapy for elderly patients with breast cancer.
        Am Surg. 1994; 60: 72-78
        • Margolese R
        • Foster R
        Tamoxifen as an alternative to surgical resection for selected geriatric patients with primary breast cancer.
        Arch Surg. 1989; 124: 548-551
        • Wong J
        • Kopald K
        • Morton D
        The impact of microinvasion on axillary node metastases and survival in patients with intraductal breast cancer.
        Arch Surg. 1990; 125: 1298-1302
        • Gelber R
        • Cole B
        • Goldhirsch A
        • et al.
        Adjuvant chemotherapy plus tamoxifen compared with tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality adjusted survival.
        Lancet. 1996; 347: 1066-1071